Publications

2021

• Maluquer de Motes, C. (2021) Poxvirus cGAMP nucleases: clues and mysteries from a stolen gene. PLoS Pathogens 17(3):1009372. DOI: 10.1371/journal.ppat.1009372

2020

• Barrado-Gil L, Del Puerto A, Munoz-Moreno R, Galindo I, Cuesto-Geijo MA, Urquiza J, Nistal-Villan E, Maluquer de Motes C, ALonso C. (2020) African swine fever virus ubiquitin-conjugating enzyme interacts with host translation machinery to regulate the host protein synthesis. Frontiers in Microbiology 11:622907. DOI: 10.3389/fmicb.2020.622907

• Hernaez B, Alonso G, Georgana I, El-Jesr M, Martin R, Shair KHY, Fisher C, Sauer S, Maluquer de Motes C, Alcami A. (2020) Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection. Science Advances 6, eabb4565. DOI: 10.1126/sciadv.abb4565

• El-Jesr M, Teir M, Maluquer de Motes C. (2020) Vaccinia virus activation and antagonism of cytosolic DNA sensing. Frontiers in Immunology 11:568412. DOI: 10.3389/fimmu.2020.568412

• Georgana I and Maluquer de Motes C. (2020) Cullin-5 adaptor SPSB1 controls NF-kB activation downstream of multiple signalling pathways. Frontiers in Immunology 10, 3121 DOI:10.3389/fimmu.2019.03121

• Gutierrez-Merino J, Isla B, Combes T, Martinez-Estrada F, Maluquer de Motes C. (2020) Beneficial bacteria activate type-I interferon production via the intracellular cytosolic sensors STING and MAVS. Gut Microbes 11, 771-778 DOI:10.1080/19490976.2019.1707015

2019

• Pallett MA, Ren H, Zhang RY, Scutts SR, Gonzalez L, Zhu Z, Maluquer de Motes C, Smith GL. (2019) Vaccinia virus BBK E3 ligase adaptor A55 targets importin-dependent NF-kB activation and inhibits CD8+ T-cell memory.  Journal of Virology 93(10):e00051-19 doi: 10.1128/JVI.00051-19

• Holmes V, Maluquer de Motes C, Richards PT, Roldan J, Bhargava AK, Orange JS, Krummenacher C. (2019) Interaction between nectin-1 and the human natural killer cell receptor CD96. PLoS ONE 14(2):e0212443. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212443

2018

• Odon V, Georgana I, Holley J, Morata J, Maluquer de Motes C. (2018) A novel class of viral Ankyrin proteins targeting the host E3 ligase Cullin-2. Journal of Virology 92(23):e01374-18. doi: 10.1128/JVI.01374-18

• Stedman A, Maluquer de Motes C, Lesellier S, Dalley D, Chamber M, Gutierrez-Merino J. (2018) Lactic acid bacteria isolated from European badgers (Meles meles) reduce the viability and survival of Bacillus Calmette-Guerin (BCG) vaccine and influence the immune response to BCG in a human macrophage model. BMC Microbiol 18(1):74. https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-018-1210-z

• Georgana I, Sumner RP, Towers GJ, Maluquer de Motes C. (2018) Virulent poxviruses inhibit DNA sensing by preventing STING activation. Journal of Virology (Feb 28) doi: 10.1128/JVI.02145-17. http://jvi.asm.org/content/92/10/e02145-17.long

2017

• Maluquer de Motes C, Smith GL. (2017) Vaccinia virus protein A49 activates Wnt signalling by targeting the E3 ligase b-TrCP. J Gen Virol (Oct 17) doi: 10.1099/jgv.0.000946. http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000946

• Veyer DL, Carrara G, Maluquer de Motes C, Smith GL. (2017) Vaccinia virus evasion of regulated cell death. Immunol Lett 186:68-80. http://www.sciencedirect.com/science/article/pii/S0165247817300548

2016

• Zeng Z, Zhang J, Jing S, Cheng Z, Bofill-Mas S, Maluquer de Motes C, Hundesa A, Girones R, Seto D, Zhang Q. (2016) Genome sequence of a Cynomolgus macaque adenovirus (CynAdV-1) from a primate colony in the United Kingdom. Genome Announc 4:e01193. http://genomea.asm.org/content/4/6/e01193-16

2015

• Neidel S, Maluquer de Motes C, Mansur DS, Strnadova P, Smith GL, Graham SC. (2015) Vaccinia virus protein A49 is an unexpected member of the B-cell lymphoma (Bcl)-2 protein family. J Biol Chem 290:5991-6002. http://www.jbc.org/content/290/10/5991.long

• Ren H, Ferguson BJ, Maluquer de Motes C, Sumner RP, Harman LE, Smith GL. (2015) Enhancement of CD8(+) T-cell memory by removal of a vaccinia virus nuclear factor kB inhibitor. Immunology 145:34-49. http://onlinelibrary.wiley.com/doi/10.1111/imm.12422/full

2014

• Veyer DL, Maluquer de Motes C, Sumner RP, Ludwig L, Johnson BF, Smith GL. (2014) Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infection. J Gen Virol 95:2757-68. http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.068833-0#tab2

• Maluquer de Motes C, Schiffner T, Sumner RP, Smith GL. (2014) Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues. J Gen Virol 95:2038-2049. http://vir.sgmjournals.org/content/95/Pt_9/2038

• Rodriguez-Manzano J, Hundesa A, Calgua B, Carratala A, Maluquer de Motes C, Rusiñol M, Girones R, Bofill-Mas S, Moresco V, Ramos AP, Monte Barardi CR, Martínez-Marca F, Calvo M. (2014) Adenovirus and Norovirus Contaminants in Commercially Distributed Shellfish. Food Environ Virol 6:31-41. http://link.springer.com/article/10.1007%2Fs12560-013-9133-1

• Sumner RP, Maluquer de Motes C, Veyer DL, Smith GL. (2014) Vaccinia virus inhibits NF-κB-dependent gene expression downstream of p65 translocation. Journal of Virology 88:3092-3102. http://jvi.asm.org/content/88/6/3092

2013

• Smith GL, Benfield CTO, Maluquer de Motes C, Mazzon M, Ember SWJ, Ferguson BJ, Sumner RP. (2013) Vaccinia virus immune evasion: Mechanisms, virulence and immunogenicity. J Gen Virol 94:2367-2392. http://vir.sgmjournals.org/content/94/Pt_11/2367

• Saraiva N, Prole DL, Carrara G, Maluquer de Motes C, Johnson BF, Byrne B, Taylor CW, Smith GL. (2013) Human and viral Golgi anti-apoptotic proteins (GAAPs) oligomerize via different mechanisms and monomeric GAAP inhibits apoptosis and modulates calcium. J Biol Chem 288:13057-13067. http://www.jbc.org/content/288/18/13057

• Mansur DS, Maluquer de Motes C, Unterholzner L, Sumner RP, Ferguson BJ, Ren H, Strnadova P, Bowie AG, Smith GL. (2013) Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence. PLoS Pathogens 9:e1003183. http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1003183

2012

• Maluquer de Motes C, Girones R, Espinosa J-C, Esteban A, Torres JM, Calvo M. (2012) Persistence of the bovine spongiform encephalopathy infectious agent in sewage. Environ Res 117:1-7. http://www.sciencedirect.com/science/article/pii/S0013935112001934

2011

• Maluquer de Motes C, Cooray S, Ren H, Almeida GM, McGourty K, Bahar MW, Stuart DI, Grimes JM, Graham SC, Smith GL. (2011) Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence. PLoS Pathog 7:e1002430. http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002430

• Maluquer de Motes C, Hundesa A, Almeida FC, Bofill-Mas S, Girones R. (2011) ‘Isolation of a novel monkey adenovirus reveals a new phylogenetic clade in the evolutionary history of simian adenoviruses’. Virol J 8:125. http://www.virologyj.com/content/8/1/125

• Bofill-Mas S, Hundesa A, Calgua B, Rusiñol M, Maluquer de Motes C, Girones R. (2011) Cost-effective method for microbial source tracking using specific human and animal viruses. J Vis Exp 3, pii 2820. http://www.jove.com/video/2820/cost-effective-method-for-microbial-source-tracking-using-specific?id=2820

2010

• Hundesa A, Bofill-Mas S, Maluquer de Motes C, Rodriguez-Manzano J, Girones R, Bach A, Casas M. (2010) Development of a quantitative PCR assay for the quantitation of bovine polyomavirus as a microbial source-tracking tool. J Virol Methods 163:385-389. http://www.sciencedirect.com/science/article/pii/S0166093409004686

2009

• Hundesa A, Maluquer de Motes C, Albinana-Gimenez N, Rodriguez-Manzano J, Bofill-Mas S, Rosina Girones R, Suñen E. (2009) Development of a qPCR assay for the quantification of porcine adenoviruses as an MST tool for swine fecal contamination in the environment. J Virol Methods 158:130-135. http://www.sciencedirect.com/science/article/pii/S0166093409000615

2008

• Maluquer De Motes C, Girones R, Simon S, Grassi J, Torres JM, Pumarola M. (2008) Assessing the presence of BSE and scrapie in slaughterhouse wastewater. J Appl Microbiol 105:1649-1657. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2672.2008.03916.x/abstract

• Maluquer de Motes C, Grassi J, Simon S, Herva ME, Torres JM, Pumarola M, Girones R. (2008) Excretion of BSE and scrapie prions in stools from murine models. Vet Microbiol 131:205-211. http://www.sciencedirect.com/science/article/pii/S0378113508000874

• Maluquer de Motes C, Cano MJ, Torres JM, Pumarola M, Girones R. (2008) Detection and survival of prion agents in aquatic environments. Water Res 42:2465-2472. http://www.sciencedirect.com/science/article/pii/S0043135408000559

2006

• Hundesa A, Maluquer de Motes C, Bofill-Mas S, Albinana-Gimenez N, Girones R. (2006) Identification of human and animal adenoviruses and polyomaviruses for determination of sources of fecal contamination in the environment. Appl Environ Microbiol 72:7886-7893. http://aem.asm.org/content/72/12/7886

2004

• Maluquer de Motes C, Clemente-Casares P, Hundesa A, Martin M, Girones R. (2004) Detection of bovine and porcine adenoviruses for tracing the source of fecal contamination. Appl Environ Microbiol 70:1448-1454. http://aem.asm.org/content/70/3/1448